A method and device for delivering medicament such as for ameliorating pain in a patient from an injector superiorly and/or laterally and/or anteriorly towards the sphenopalatine ganglion (SPG). A device for delivering a medicament to a patient in need thereof includes (a) an injector containing a first end configured to remain outside a nasal passage of the patient and a second end configured for entry into the nasal passage of the patient; and (b) an introducer configured for engagement with a nostril of the patient and containing a passageway configured for slidably receiving the injector. The injector is moveable between a storage position preceding the engagement and an engaging position pursuant to the engagement. The device may further include a locking connection assembly that is useful in other devices.