发明授权
US08691211B2 Suppression of immune response to factor VIII in hemophilia A patients
有权
抑制血友病A患者因子VIII的免疫反应
- 专利标题： Suppression of immune response to factor VIII in hemophilia A patients
- 专利标题（中）： 抑制血友病A患者因子VIII的免疫反应
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申请号： US12721361申请日： 2010-03-10
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公开(公告)号： US08691211B2公开(公告)日： 2014-04-08
- 发明人: Neil Cary Josephson
- 申请人： Neil Cary Josephson
- 申请人地址： US WA Seattle
- 专利权人： Puget Sound Blood Center
- 当前专利权人： Puget Sound Blood Center
- 当前专利权人地址： US WA Seattle
- 代理机构： Fenwick & West LLP
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K38/37 ; C12N5/10 ; C12N15/85
摘要：
This invention relates to methods and compositions for suppressing an immune response to Factor VIII in subjects suffering from hemophilia A and having preformed inhibitor antibodies against Factor VIII, and compositions and methods that advantageously render subjects amenable to standard treatments for hemophilia A, including Factor VIII replacement therapy.
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