发明授权
US08691227B2 Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α 有权
使用PILR-α的激动剂抗体治疗多发性硬化,类风湿性关节炎和炎症性肠病的方法

  • 专利标题: Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
  • 专利标题(中): 使用PILR-α的激动剂抗体治疗多发性硬化,类风湿性关节炎和炎症性肠病的方法
  • 申请号: US13516635
    申请日: 2010-12-10
  • 公开(公告)号: US08691227B2
    公开(公告)日: 2014-04-08
  • 发明人: Cristina M. TatoBarbara Joyce-ShaikhDaniel J. Cua
  • 申请人: Cristina M. TatoBarbara Joyce-ShaikhDaniel J. Cua
  • 申请人地址: US NJ Rahway
  • 专利权人: Merck Sharp & Dohme Corp.
  • 当前专利权人: Merck Sharp & Dohme Corp.
  • 当前专利权人地址: US NJ Rahway
  • 代理商 Gregory R. Bellomy
  • 国际申请: PCT/US2010/059893 WO 20101210
  • 国际公布: WO2011/084357 WO 20110714
  • 主分类号: A61K39/00
  • IPC分类号: A61K39/00
Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
摘要:
The present invention provides methods of using PILRα agonists, or PILRβ antagonists, to treat immune disorders, such as autoimmune and inflammatory disorders, including CNS, joint and gut inflammation.
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