发明授权
US08691227B2 Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
有权
使用PILR-α的激动剂抗体治疗多发性硬化,类风湿性关节炎和炎症性肠病的方法
- 专利标题: Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
- 专利标题(中): 使用PILR-α的激动剂抗体治疗多发性硬化,类风湿性关节炎和炎症性肠病的方法
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申请号: US13516635申请日: 2010-12-10
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公开(公告)号: US08691227B2公开(公告)日: 2014-04-08
- 发明人: Cristina M. Tato , Barbara Joyce-Shaikh , Daniel J. Cua
- 申请人: Cristina M. Tato , Barbara Joyce-Shaikh , Daniel J. Cua
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 代理商 Gregory R. Bellomy
- 国际申请: PCT/US2010/059893 WO 20101210
- 国际公布: WO2011/084357 WO 20110714
- 主分类号: A61K39/00
- IPC分类号: A61K39/00
摘要:
The present invention provides methods of using PILRα agonists, or PILRβ antagonists, to treat immune disorders, such as autoimmune and inflammatory disorders, including CNS, joint and gut inflammation.
公开/授权文献
- US20130071380A1 MODULATION OF PILR TO TREAT IMMUNE DISORDERS 公开/授权日:2013-03-21
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