发明授权
US08691246B2 Composition for forming a temporary intestinal occlusion in a mammal
有权
用于在哺乳动物中形成临时肠闭塞的组合物
- 专利标题: Composition for forming a temporary intestinal occlusion in a mammal
- 专利标题(中): 用于在哺乳动物中形成临时肠闭塞的组合物
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申请号: US13547619申请日: 2012-07-12
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公开(公告)号: US08691246B2公开(公告)日: 2014-04-08
- 发明人: Georg Bischof
- 申请人: Georg Bischof
- 代理机构: Drinker Biddle & Reath LLP
- 优先权: AT1026/2011 20110713
- 主分类号: A61K31/718
- IPC分类号: A61K31/718 ; A61K9/00
摘要:
A composition for forming a temporary intestinal occlusion in a mammal is flowable and solidifiable to form a solid plug at a predetermined site in the intestine, the structure of the plug being changeable to allow for a subsequent, at least partial removal of the occlusion. The composition is or comprises a flowable solution, suspension, or dispersion in a solvent or mixed solvent, and comprises the following: a) a suspension of a solid in water or an aqueous mixed solvent, the suspension having a water content which exceeds the flow limit of the suspension by a specific amount; b) a dehydrating agent in an amount which is sufficient to bind the specific amount of water, so that, as a consequence of dehydration, the flow limit of the suspension is exceeded; and c) a means for passivating the dehydrating agent.
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