发明授权
US08691262B2 Method for aligning cells and applying homogenous strain throughout deformable engineered tissue constructs
有权
在整个可变形工程组织构建体中对齐细胞并应用均质菌株的方法
- 专利标题: Method for aligning cells and applying homogenous strain throughout deformable engineered tissue constructs
- 专利标题(中): 在整个可变形工程组织构建体中对齐细胞并应用均质菌株的方法
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申请号: US13568057申请日: 2012-08-06
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公开(公告)号: US08691262B2公开(公告)日: 2014-04-08
- 发明人: Matthew Thomas Harris
- 申请人: Matthew Thomas Harris
- 申请人地址: US AZ Tucson
- 专利权人: Matthew Thomas Harris
- 当前专利权人: Matthew Thomas Harris
- 当前专利权人地址: US AZ Tucson
- 主分类号: A61F2/02
- IPC分类号: A61F2/02
摘要:
A process creates a homogenous sheet of engineered tissue comprised of encapsulated cells and a deformable engineered tissue construct. In the embodiment consisting of a collagen construct with encapsulated cells capable of contracting the matrix, the collagen fibers and encapsulated cells are aligned during the process. An apparatus can deliver controlled homogenous strain and stress to a thin sheet of engineered tissue. This process allows application of dynamic, uniform tensile loading to deformable engineered tissue constructs and creation of an engineered cell-delivery construct with alignment of both fibers and encapsulated cells.
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