Invention Grant
- Patent Title: Ingestible formulations for transient, noninvasive reduction of gastric volume
- Patent Title (中): 用于瞬时,无创减少胃体积的可食用制剂
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Application No.: US12148702Application Date: 2008-01-25
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Publication No.: US08691271B2Publication Date: 2014-04-08
- Inventor: Daniel R. Burnett , Peter G. Edelman
- Applicant: Daniel R. Burnett , Peter G. Edelman
- Applicant Address: US CA Goleta
- Assignee: BAROnova, Inc.
- Current Assignee: BAROnova, Inc.
- Current Assignee Address: US CA Goleta
- Agency: Levine Bagade Han LLP
- Main IPC: A61K9/20
- IPC: A61K9/20 ; A61K9/00 ; A61K9/28 ; A61K9/48 ; A61F5/00

Abstract:
Provided are ingestible polymeric formulations and oral dosage forms for the reduction of gastric volume in the treatment of overweight and obese patients. The formulation includes an acid-sensitive, gelatin coating over a dehydrated hydrophilic polymer. When ingested, the acid-sensitive coating is quickly dissolved by gastric secretions and the hydrophilic polymer is exposed to the aqueous environment of the gastric milieu. The polymer absorbs water and expands to the point that will not allow the polymer to pass beyond the pyloric valve, and the expanded polymer is therefore trapped in the stomach.
Public/Granted literature
- US20080241094A1 Ingestible formulations for transient, noninvasive reduction of gastric volume Public/Granted day:2008-10-02
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