发明授权
US08691780B2 Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby
失效
Txr1和增强的紫杉烷敏感性基于由其介导的途径的调节
- 专利标题： Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby
- 专利标题（中）： Txr1和增强的紫杉烷敏感性基于由其介导的途径的调节
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申请号： US11357728申请日： 2006-02-16
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公开(公告)号： US08691780B2公开(公告)日： 2014-04-08
- 发明人: Chih Jian Lih , Stanley N. Cohen
- 申请人： Chih Jian Lih , Stanley N. Cohen
- 申请人地址： US CA Palo Alto
- 专利权人： The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人： The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人地址： US CA Palo Alto
- 代理机构： Bozicevic, Field & Francis LLP
- 代理商 Bret E. Field; Kyle A. Gurley
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; A61K31/337 ; A61K31/341
摘要：
Methods and compositions for enhancing taxane sensitivity are provided. Aspects of the subject methods include administering to a subject a txr1 pathway modulatory agent in conjunction with a taxane. Also provided are txr1 polypeptides and nucleic acids encoding the same. The subject methods and compositions find use in a variety of different applications.