Invention Grant
US08691986B2 Azetidine and piperidine compounds useful as PDE10 inhibitors
有权
可用作PDE10抑制剂的氮杂环丁烷和哌啶化合物
- Patent Title: Azetidine and piperidine compounds useful as PDE10 inhibitors
- Patent Title (中): 可用作PDE10抑制剂的氮杂环丁烷和哌啶化合物
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Application No.: US13917699Application Date: 2013-06-14
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Publication No.: US08691986B2Publication Date: 2014-04-08
- Inventor: Jennifer R. Allen , Jian J. Chen , Michael J. Frohn , Matthew R. Kaller , Qingyian Liu , Thomas T. Nguyen , Alexander J. Pickrell , Wenyuan Qian , Robert M. Rzasa , Wenge Zhong
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- Main IPC: C07D241/00
- IPC: C07D241/00 ; C07D239/70 ; C07D471/02 ; C07D215/00

Abstract:
Azetidine and piperidine compounds of formula (I): as defined in the specification, compositions containing them, and processes for preparing such compounds and intermediates thereof. Provided herein also are methods of treating cognitive disorders or diseases treatable by inhibition of PDE10, such as Huntington's Disease, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
Public/Granted literature
- US20130338138A1 AZETIDINE AND PIPERIDINE COMPOUNDS USEFUL AS PDE10 INHIBITORS Public/Granted day:2013-12-19
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