A cargo screen of a vehicle luggage room, the cargo screen may include a housing mounted at an upper portion of the vehicle luggage room in a horizontal direction and having a central portion to be foldable, a roller rotatably installed in the housing and having a cut central portion to be foldable, and a screen wound around an outer peripheral surface of the roller in the housing through a cut hole thereof or selectively unwound to the outside of the housing to cover the vehicle luggage room, and having a cut central portion to be foldable.