To provide a graphene sheet that has a large area, is homogeneous, and has a small amount of domain boundaries, a novel method for producing a graphene sheet suitable for industrial applications, such as application to electronics, that is capable of producing a graphene sheet that has well aligned crystal orientation at a low cost, and a graphene sheet.In the method for producing a graphene sheet of the present invention, a substrate containing a single crystal substrate having formed on the surface thereof an epitaxial metal film is used, and a graphene sheet is grown by making a carbon material into contact with the surface of the epitaxial metal film. In the graphene sheet of the present invention, the graphene sheet is constituted by a number of graphene domains, the domains each have an area of from 0.000001 μm2 to 100,000 mm2, and the orientations of 6-membered rings in the domains are averagely aligned in a single direction over the graphene sheet.