Invention Grant
- Patent Title: Anti-cancer drug screening method using RORα
- Patent Title (中): 使用RORα的抗癌药物筛选方法
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Application No.: US13143676Application Date: 2010-01-08
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Publication No.: US08697366B2Publication Date: 2014-04-15
- Inventor: Keun Il Kim , Ji Min Lee , Sung Hee Baek
- Applicant: Keun Il Kim , Ji Min Lee , Sung Hee Baek
- Applicant Address: KR Seoul
- Assignee: Seoul National University Industry Foundation
- Current Assignee: Seoul National University Industry Foundation
- Current Assignee Address: KR Seoul
- Agency: Clark & Elbing LLP
- Priority: KR10-2009-0001519 20090108
- International Application: PCT/KR2010/000132 WO 20100108
- International Announcement: WO2010/079994 WO 20100715
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/574
Abstract:
The present invention relates to a method for screening an anticancer agent using RORα, the method comprising the steps of: culturing cells; bringing a potential substance into contact with the cells; determining whether the phosphorylation level of RORα in the cells increases as compared to that in control cells (not brought into contact with the potential substance); and selecting the potential substance as an anticancer agent if the phosphorylation level of RORα in the cells increases.
Public/Granted literature
- US20110294130A1 Anti-Cancer Drug Screening Method Using ROR-alpha Public/Granted day:2011-12-01
Information query
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