发明授权
US08697731B2 Derivatives of 2-pyridin-2-yl-pyrazol-3(2H)-one, preparation and therapeutic use thereof
有权
2-吡啶-2-基 - 吡唑-3（2H） - 酮的衍生物，其制备和治疗用途
- 专利标题： Derivatives of 2-pyridin-2-yl-pyrazol-3(2H)-one, preparation and therapeutic use thereof
- 专利标题（中）： 2-吡啶-2-基 - 吡唑-3（2H） - 酮的衍生物，其制备和治疗用途
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申请号： US13172321申请日： 2011-06-29
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公开(公告)号： US08697731B2公开(公告)日： 2014-04-15
- 发明人: Jean-Michel Altenburger , Valérie Fossey , Stéphane Illiano , Géraldine Manette
- 申请人： Jean-Michel Altenburger , Valérie Fossey , Stéphane Illiano , Géraldine Manette
- 申请人地址： FR Paris
- 专利权人： Sanofi
- 当前专利权人： Sanofi
- 当前专利权人地址： FR Paris
- 代理机构： Scully, Scott, Murphy & Presser, P.C.
- 优先权： FR0807475 20081229; FR0904091 20090828
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D401/04
摘要：
The invention relates to compounds corresponding to formula (I), in the form of the base or of an acid-addition salt: in which n is equal to 0, 1, 2, 3 or 4; m is equal to 0, 1 or 2; o is equal to 0 or 1; X represents a group —CH2, —CH(R′)—, —NH(R′)— or a heteroatom chosen from O and S, it being understood that R′ represents a group —(C1-C5)alkyl, —(C1-C5)alkoxy, —CH2-aryl, —C(O)R5 or —COOR5; R1, R2, R5 are as defined in the specification.