发明授权
- 专利标题: Substrate for Rpn 11 enzymatic activity
- 专利标题(中): 用于Rpn 11酶活性的底物
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申请号: US12505984申请日: 2009-07-20
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公开(公告)号: US08697837B2公开(公告)日: 2014-04-15
- 发明人: Francesco Parlati , Monette Aujay , Mark K. Bennett
- 申请人: Francesco Parlati , Monette Aujay , Mark K. Bennett
- 申请人地址: US CA South San Francisco
- 专利权人: Onyx Therapeutics, Inc.
- 当前专利权人: Onyx Therapeutics, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: Marshall, Gerstein & Borun LLP
- 主分类号: C07K14/00
- IPC分类号: C07K14/00
摘要:
The present application provides peptides that serve as substrates for proteasome enzymatic activity, e.g., the enzymatic activity of Rpn11, a metalloprotease of the 19S regulatory particle. The present application also provides methods and compositions employing the peptide substrates.
公开/授权文献
- US20100196346A1 NOVEL SUBSTRATE FOR RPN 11 ENZYMATIC ACTIVITY 公开/授权日:2010-08-05
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