发明授权
- 专利标题: High affinity T cell receptor and use thereof
- 专利标题(中): 高亲和力T细胞受体及其用途
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申请号: US13130665申请日: 2009-11-24
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公开(公告)号: US08697854B2公开(公告)日: 2014-04-15
- 发明人: Dolores Schendel , Susanne Wilde , Bernhard Frankenberger , Wolfgang Uckert
- 申请人: Dolores Schendel , Susanne Wilde , Bernhard Frankenberger , Wolfgang Uckert
- 申请人地址: DE Neuherberg
- 专利权人: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH
- 当前专利权人: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH
- 当前专利权人地址: DE Neuherberg
- 代理机构: Jenkins, Wilson, Taylor & Hunt, P.A.
- 优先权: EP08020396 20081124
- 国际申请: PCT/EP2009/065705 WO 20091124
- 国际公布: WO2010/058023 WO 20100527
- 主分类号: C07K14/725
- IPC分类号: C07K14/725 ; C12N15/12
摘要:
The present invention is directed to a high affinity T cell receptor (TCR) against a tumor-associated antigen, an isolated nucleic acid molecule encoding same, a T cell expressing said TCR, and a pharmaceutical composition for use in the treatment of diseases involving malignant cells expressing said tumor-associated antigen.
公开/授权文献
- US20110280889A1 HIGH AFFINITY T CELL RECEPTOR AND USE THEREOF 公开/授权日:2011-11-17
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