A system and method is disclosed for calibrating a pointing device. A virtual movement of a position indicator is generated based on current acceleration parameters of an acceleration curve applied to a physical movement made at a pointing device and terminating at a target action. A plurality of virtual path segments are determined based on the physical movement, and an overall error representative of a deviation of the endpoint of each segment from the target action is generated. One or more hypothetical acceleration parameters are calculated that, when applied to the changing position information, generate an overall hypothetical error value less than the overall error. The current acceleration parameters are set equal to the one or more hypothetical acceleration parameters to calibrate the pointing device.