发明授权
US08703796B2 3H-imidazo [4, 5-B] pyridine-6-carboxamides as anti-inflammatory agents
失效
3H-咪唑并[4,5-B]吡啶-6-甲酰胺作为抗炎剂
- 专利标题: 3H-imidazo [4, 5-B] pyridine-6-carboxamides as anti-inflammatory agents
- 专利标题(中): 3H-咪唑并[4,5-B]吡啶-6-甲酰胺作为抗炎剂
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申请号: US13119836申请日: 2009-09-25
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公开(公告)号: US08703796B2公开(公告)日: 2014-04-22
- 发明人: Roland Pfau , Kirsten Arndt , Henri Doods , Norbert Hauel , Klaus Klinder , Raimund Kuelzer
- 申请人: Roland Pfau , Kirsten Arndt , Henri Doods , Norbert Hauel , Klaus Klinder , Raimund Kuelzer
- 申请人地址: DE Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim am Rhein
- 代理商 Michael P. Morris; Philip I. Datlow
- 优先权: EP08165120 20080925
- 国际申请: PCT/EP2009/062425 WO 20090925
- 国际公布: WO2010/034799 WO 20100401
- 主分类号: A01N43/42
- IPC分类号: A01N43/42 ; A61K31/44 ; C07D471/02 ; C07D491/02 ; C07D498/02
摘要:
There are provided compounds of formula (I), wherein R1, R6, R8, Q2, Q3, Q3a, Q4, L and A have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation and/or cancer.