Isolated nucleotide sequences encoding GDF traps

Invention Grant

US08703927B2 Isolated nucleotide sequences encoding GDF traps 有权

Title translation: 分离的编码GDF陷阱的核苷酸序列

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Patent Title: Isolated nucleotide sequences encoding GDF traps
Patent Title (中): 分离的编码GDF陷阱的核苷酸序列
Application No.: US13542269

Application Date: 2012-07-05
Publication No.: US08703927B2

Publication Date: 2014-04-22
Inventor: Jasbir Seehra , Robert Scott Pearsall , Ravindra Kumar
Applicant: Jasbir Seehra , Robert Scott Pearsall , Ravindra Kumar
Applicant Address: US MA Cambridge
Assignee: Acceleron Pharma Inc.
Current Assignee: Acceleron Pharma Inc.
Current Assignee Address: US MA Cambridge
Agency: Ropes & Gray LLP
Main IPC: C07H21/04
IPC: C07H21/04

Isolated nucleotide sequences encoding GDF traps

Abstract:

In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.

Abstract(Chinese):

在某些方面，本发明提供用于增加脊椎动物（包括啮齿动物和灵长类动物，特别是人）中红细胞和/或血红蛋白水平的组合物和方法。

Public/Granted literature

US20130071393A1 METHODS FOR INCREASING RED BLOOD CELL LEVELS AND TREATING ANEMIA USING A COMBINATION OF GDF TRAPS AND ERYTHROPOIETIN RECEPTOR ACTIVATORS Public/Granted day:2013-03-21

Information query

Espacenet

IPC分类:

C	化学；冶金
C07	有机化学
C07H	糖类；及其衍生物；核苷；核苷酸；核酸（糖醛酸或糖质酸的衍生物入C07C、C07D；糖醛酸、糖质酸入C07C59/105，C07C59/285；氰醇类入C07C255/16；烯糖类入C07D；未知结构的化合物入C07G；多糖类，有关的衍生物入C08B；有关基因工程的DNA或RNA，载体，例如质粒，或它们的分离、制备或纯化入C12N15/00；制糖工业入C13）
C07H21/00	含有两个或多个单核苷酸单元的化合物，具有以核苷基的糖化物基团连接的单独的磷酸酯基或多磷酸酯基，例如核酸
C07H21/04	.有脱氧核糖基作为糖化物基团的