发明授权
- 专利标题： Method for analyzing cervical lymph node metastasis, and tumor marker for head and neck cancer
- 专利标题（中）： 分析颈淋巴结转移的方法和头颈癌的肿瘤标志物
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申请号： US13518656申请日： 2010-12-22
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公开(公告)号： US08715931B2公开(公告)日： 2014-05-06
- 发明人: Koichi Nakashiro , Hiroyuki Hamakawa , Hiroyuki Goda
- 申请人： Koichi Nakashiro , Hiroyuki Hamakawa , Hiroyuki Goda
- 申请人地址： JP Ehime
- 专利权人： National University Corporation Ehime University
- 当前专利权人： National University Corporation Ehime University
- 当前专利权人地址： JP Ehime
- 代理机构： Morgan, Lewis & Bockius LLP
- 优先权： JP2009-292611 20091224
- 国际申请： PCT/JP2010/073129 WO 20101222
- 国际公布： WO2011/078223 WO 20110630
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Provided are a method for analyzing metastasis of head and neck cancer to a cervical lymph node, and a tumor marker for head and neck cancer used therein. Specifically, provided is a method for analyzing metastasis of head and neck cancer to a cervical lymph node, involving: measuring an expression level of at least one gene selected from the group consisting of genes represented by SEQ ID NOS: 1 to 36 in the sequence listing in a cervical lymph node sample; and comparing the aforementioned expression level with a reference value. Also provided is a tumor marker for head and neck cancer used in the aforementioned method for analyzing cervical lymph node metastasis, including at least one gene selected from the group consisting of genes represented by SEQ ID NOS: 1 to 36 in the sequence listing, and/or an expression product of the aforementioned gene and/or an expression level thereof.