发明授权
- 专利标题： Modified exendins and uses thereof
- 专利标题（中）： 改良的exendins及其用途
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申请号： US13334912申请日： 2011-12-22
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公开(公告)号： US08716221B2公开(公告)日： 2014-05-06
- 发明人: Aifeng Lv , Changan Sun , Yali Wang
- 申请人： Aifeng Lv , Changan Sun , Yali Wang
- 申请人地址： CN Jiangsu
- 专利权人： Wuxi Grandchamp Pharmaceutical Technology Co., Ltd.
- 当前专利权人： Wuxi Grandchamp Pharmaceutical Technology Co., Ltd.
- 当前专利权人地址： CN Jiangsu
- 代理机构： Norris McLaughlin & Marcus, P.A.
- 优先权： CN200510038102 20050114
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/26
摘要：
The present invention discloses a modified exendin or pharmaceutically acceptable salts thereof, wherein the modified exendin comprises an amino acid sequence having at least 90% sequence identity to SEQ ID No. 17 and the amino acid sequence has a higher stability than the non-modified exendin of SEQ ID No. 4. These compounds are useful in treating type 2 diabetes as GLP-1 receptor agonists.
公开/授权文献
- US20120196802A1 MODIFIED EXENDINS AND USES THEREOF 公开/授权日：2012-08-02