Cloud infrastructure of an information processing system comprises one or more processing devices implementing a plurality of virtual machines. The cloud infrastructure is configured to receive a processing job from a tenant, to obtain a first key specific to the tenant, to determine a second key utilizing information supplied by the tenant, and to encrypt one or more results of the processing job utilizing a combination of the first key and the second key. At least a portion of the second key is determined by at least one application that is run on at least one virtual machine of the cloud infrastructure in conjunction with performance of the processing job. The encrypted results of the processing job may be stored in a virtual memory of the cloud infrastructure and transmitted to the tenant.