Invention Grant
- Patent Title: IL4/IL13 binding repeat proteins and uses
- Patent Title (中): IL4 / IL13结合重复蛋白和用途
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Application No.: US13458578Application Date: 2012-04-27
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Publication No.: US08722618B2Publication Date: 2014-05-13
- Inventor: Steven Jacobs , Karyn O'Neil , Michael Baumann , Gaby Sennhauser
- Applicant: Steven Jacobs , Karyn O'Neil , Michael Baumann , Gaby Sennhauser
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agent Eric Dichter
- Main IPC: C12N15/24
- IPC: C12N15/24 ; C07K14/00 ; A61P11/00 ; A61P11/06 ; A61P9/00 ; A61P35/00 ; C12P21/02 ; C12N15/11 ; C12N15/63 ; C12N1/21 ; C12N1/19 ; C12N7/01 ; C12N5/10 ; A61K38/16 ; A61P17/00
Abstract:
IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpaha and common gamma chain complexes (Type 1) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions.
Public/Granted literature
- US20120277143A1 IL4/IL13 Binding Repeat Proteins and Uses Public/Granted day:2012-11-01
Information query
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