发明授权
US08722882B2 Pyrimidine derivatives as GPCR modulators for use in the treatment of obesity and diabetes
有权
嘧啶衍生物作为用于治疗肥胖和糖尿病的GPCR调节剂
- 专利标题： Pyrimidine derivatives as GPCR modulators for use in the treatment of obesity and diabetes
- 专利标题（中）： 嘧啶衍生物作为用于治疗肥胖和糖尿病的GPCR调节剂
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申请号： US13141227申请日： 2009-12-21
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公开(公告)号： US08722882B2公开(公告)日： 2014-05-13
- 发明人: Bernard R. Neustadt , Andrew Stamford , Jinsong Hao , Charles Lee Jayne , Yan Xia
- 申请人： Bernard R. Neustadt , Andrew Stamford , Jinsong Hao , Charles Lee Jayne , Yan Xia
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Anna L. Cocuzzo; Catherine D. Fitch
- 国际申请： PCT/US2009/068968 WO 20091221
- 国际公布： WO2010/075269 WO 20100701
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; C07D401/14 ; C07D471/08 ; A61K31/506 ; A61P3/04 ; A61P3/10
摘要：
The present invention relates to Pyriraidine Derivatives of formula (I), compositions comprising a Pyrimidine Derivative, and methods of using the Pyrimidine Derivatives for treating or preventing obesity, diabetes, a diabetic complication, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a G protein-coupled receptor (GPCR) in a patient.
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