发明授权
US08722939B2 Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis
有权
用于治疗肌萎缩性侧索硬化症的环己烷-1,3-二酮
- 专利标题: Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis
- 专利标题(中): 用于治疗肌萎缩性侧索硬化症的环己烷-1,3-二酮
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申请号: US13504893申请日: 2010-10-29
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公开(公告)号: US08722939B2公开(公告)日: 2014-05-13
- 发明人: Donald R. Kirsch , Radhia Benmohamed , Anthony C. Arvanites , Richard I. Morimoto , Wei Zhang , Richard B. Silverman
- 申请人: Donald R. Kirsch , Radhia Benmohamed , Anthony C. Arvanites , Richard I. Morimoto , Wei Zhang , Richard B. Silverman
- 申请人地址: US IL Evanston US MA Cambridge
- 专利权人: Northwestern University,Cambria Pharmaceuticals, Inc.
- 当前专利权人: Northwestern University,Cambria Pharmaceuticals, Inc.
- 当前专利权人地址: US IL Evanston US MA Cambridge
- 代理机构: Reinhart Boerner Van Deuren s.c.
- 国际申请: PCT/US2010/054747 WO 20101029
- 国际公布: WO2011/059821 WO 20110519
- 主分类号: C07C49/697
- IPC分类号: C07C49/697 ; C07C225/22 ; C07D295/205 ; A61K31/136 ; A61K31/495 ; A61K31/403
摘要:
The present invention relates to the identification of provided cyclohexane-1,3-diones (CHD compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided CHD compounds.
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