The present invention relates to a multi-input multi-output (MIMO) antenna with a multi-band characteristic which includes a plurality of MIMO antenna, each having a pair of antenna elements, to support multiple bands, and is capable of guaranteeing high antenna efficiency for different bands by minimizing an interference between antenna elements of each MIMO antenna to improve an isolation characteristic. The MIMO antenna system having a multi-band characteristic, which includes two pairs of antenna patterns to support different band and coupling antenna parts separated from and coupled with the pairs of antenna patterns, can improve an isolation through the coupling antenna parts and guarantee an antenna gain. Moreover, since signal interference caused by the coupling effect can be cancelled to guarantee a band width with no change in antenna characteristics, it is possible to constructing two or more antennas to support a multi-band while guaranteeing stable operation of the antennas.