发明授权
- 专利标题： Multivalent fibronectin based scaffold domain proteins
- 专利标题（中）： 基于多价纤连蛋白的支架结构蛋白
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申请号： US13533382申请日： 2012-06-26
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公开(公告)号： US08728483B2公开(公告)日： 2014-05-20
- 发明人: Ray Camphausen , Eric Furfine , Irvith M. Carvajal , H. Nicholas Marsh , Marco Gottardis , Joan Carboni , Ricardo Attar
- 申请人： Ray Camphausen , Eric Furfine , Irvith M. Carvajal , H. Nicholas Marsh , Marco Gottardis , Joan Carboni , Ricardo Attar
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理机构： Nelson Mullins Riley & Scarborough LLP
- 代理商 Jane E. Remillard, Esq.; Cynthia L. Kanik
- 主分类号： A61K38/39
- IPC分类号： A61K38/39 ; A61K47/48 ; C07K14/705 ; C07K14/78 ; C07K14/435
摘要：
The present invention relates to multivalent polypeptides comprising at least two fibronectin scaffold domains connected via a polypeptide linker. The invention also relates to multivalent polypeptides for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins.
公开/授权文献
- US20130012435A1 MULTIVALENT FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS 公开/授权日：2013-01-10