发明授权
- 专利标题： Microorganisms having intestinal cell surface glycosylation modulating action
- 专利标题（中）： 具有肠细胞表面糖基化调节作用的微生物
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申请号： US11281738申请日： 2005-11-16
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公开(公告)号： US08728743B2公开(公告)日： 2014-05-20
- 发明人: Jean-Michel Antoine , Miguel Freitas , Chantal Cayuela , Germain Trugnan
- 申请人： Jean-Michel Antoine , Miguel Freitas , Chantal Cayuela , Germain Trugnan
- 申请人地址： FR Levallois-Perret
- 专利权人： Compagnie Gervais Danone
- 当前专利权人： Compagnie Gervais Danone
- 当前专利权人地址： FR Levallois-Perret
- 代理机构： Patzik, Frank & Samotny Ltd.
- 优先权： FR0008672 20000704
- 主分类号： G01N33/567
- IPC分类号： G01N33/567
摘要：
The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.
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