A method and apparatus for encoding and decoding an image using a plurality of reference pictures. In an exemplary embodiment, the method of encoding an image comprises: generating information about transforms between a first picture and a second picture; generating a reference picture by transforming the second picture based on the generated information about transforms; predicting a current block of a current picture based on at least one of the reference picture and the first picture; and encoding the current block based on the predicting. Therefore, prediction encoding based on more accurate prediction is possible, thereby increasing a compression ratio of image encoding.