A method and system for managing storage of one or more data blocks in a programmable data storage device is provided. A data storage controller partitions each of multiple data blocks into multiple sub data blocks comprising a number of bits based on one or more index value descriptors. The data storage controller generates transition vectors from each of the sub data blocks by applying one or more transition functions. The data storage controller encodes one of the transition vectors for each sub data block for obtaining a residual sub data block comprising a reduced number of bits, thereby resulting in increased bit space. The data storage controller generates a composite data block by merging each residual sub data block. The composite data block is configurable for writing to one or more regions in the programmable data storage device free from a disturbance caused by write operations to other regions.