A separation system for separating a fluid mixture includes a uniaxial cyclonic separator (2) having a first inlet (16) for receiving a fluid mixture, a separation chamber (18) for separating the fluid mixture by cyclonic action into a dense first fluid and a less dense second fluid, a first outlet (22) for the first fluid and a second outlet (26) for the second fluid. The system further includes a reverse flow cyclonic separator (32) having a second inlet (30) for receiving the first fluid from the first outlet (22), a separation chamber for separating the first fluid by cyclonic action into a dense third fluid and a less dense fourth fluid, a third outlet (34) for the third fluid and a fourth outlet (36) for the fourth fluid. A method for the bulk separation of water from an oil/water mixture is also provided.