发明授权
- 专利标题: Molecules and methods for modulating TMEM16A activities
- 专利标题(中): 分子和调节TMEM16A活性的方法
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申请号: US13485311申请日: 2012-05-31
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公开(公告)号: US08748587B2公开(公告)日: 2014-06-10
- 发明人: Larry Alexander Gaither , Christopher John Rothwell
- 申请人: Larry Alexander Gaither , Christopher John Rothwell
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理商 Mei Benni
- 主分类号: C07K16/30
- IPC分类号: C07K16/30 ; C07K16/46 ; A61K39/395
摘要:
The present invention provides molecules that bind to TMEM16A (“TMEM16A binding molecules”), particularly human or humanized antibodies and antibody drug conjugates that bind to human TMEM16A and modulate its functions. Epitopes of TMEM16A and molecules that bind these epitopes are also provided herein.
公开/授权文献
- US20120308582A1 MOLECULES AND METHODS FOR MODULATING TMEM16A ACTIVITIES 公开/授权日:2012-12-06
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