A power amplification device is disclosed that includes a power amplification circuit operable to amplify a radio frequency (RF) signal in accordance with an amplification gain, and a voltage regulation circuit operable to generate a regulated voltage. A regulated voltage level of the regulated voltage sets the amplification gain. To help prevent the voltage regulation circuit from saturating, the voltage regulation circuit is configured to reduce a voltage adjustment gain when the regulated voltage level reaches a threshold voltage level. In one embodiment, the threshold voltage level is set to be higher when a band-select signal indicates that the RF signal is being transmitted within a first frequency band, and is set to be lower when the band-select signal indicates that the RF signal is being transmitted within a second frequency band. The spectral performance of the power amplification device thus improves with regard to the second frequency band.