发明授权
- 专利标题： Compositions and methods for crystallizing antibodies
- 专利标题（中）： 用于结晶抗体的组合物和方法
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申请号： US12228038申请日： 2008-08-08
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公开(公告)号： US08753839B2公开(公告)日： 2014-06-17
- 发明人: Wolfgang Fraunhofer , David W. Borhani , Gerhard Winter , Stefan Gottschalk
- 申请人： Wolfgang Fraunhofer , David W. Borhani , Gerhard Winter , Stefan Gottschalk
- 申请人地址： US IL North Chicago
- 专利权人： Abbvie Inc.
- 当前专利权人： Abbvie Inc.
- 当前专利权人地址： US IL North Chicago
- 代理机构： McCarter & English, LLP
- 代理商 Cristin H. Cowles; Soo-Hwa Kim
- 主分类号： C12P21/06
- IPC分类号： C12P21/06 ; A61K39/395 ; A01N61/00 ; C07K16/24 ; A61K39/00
摘要：
The present invention relates to a batch crystallization method for crystallizing anti-human TNFalpha (hTNFalpha) antibody and antibody fragments which allows the production of said antibody on an industrial scale; a method of controlling the size of antibody crystals, for example, crystals of anti-hTNFalpha antibody fragments, compositions containing said crystals as well as methods of use of said crystals and compositions.
公开/授权文献
- US20090148513A1 Compositions and methods for crystallizing antibodies 公开/授权日：2009-06-11
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