发明授权
- 专利标题: Method for determining protein solubility
- 专利标题(中): 测定蛋白质溶解度的方法
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申请号: US11661762申请日: 2005-09-05
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公开(公告)号: US08754012B2公开(公告)日: 2014-06-17
- 发明人: Darren James Hart
- 申请人: Darren James Hart
- 申请人地址: DE Heidelberg
- 专利权人: European Molecular Biology Laboratory
- 当前专利权人: European Molecular Biology Laboratory
- 当前专利权人地址: DE Heidelberg
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: GB0419628.3 20040903
- 国际申请: PCT/GB2005/003417 WO 20050905
- 国际公布: WO2006/024875 WO 20060309
- 主分类号: C40B20/04
- IPC分类号: C40B20/04 ; C40B20/08 ; C40B30/04
摘要:
The present invention relates to methods of screening for expression of a soluble candidate protein within an expression library of candidate proteins. The method involves fusing each candidate protein in the library to a peptide substrate and identifying cells that express soluble candidate protein by detecting enzymatic modification of the peptide substrate.
公开/授权文献
- US20080132425A1 Method for Determining Protein Solubility 公开/授权日:2008-06-05
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