发明授权
- 专利标题: Substituted piperazino-dihydrothienopyrimidines
- 专利标题(中): 取代的哌嗪基 - 二氢噻吩并嘧啶
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申请号: US12738344申请日: 2008-10-16
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公开(公告)号: US08754073B2公开(公告)日: 2014-06-17
- 发明人: Pascale Pouzet , Ralf Anderskewitz , Horst Dollinger , Dennis Fiegen , Thomas Fox , Rolf Goeggel , Christoph Hoenke , Domnic Martyres , Peter Nickolaus , Klaus Klinder
- 申请人: Pascale Pouzet , Ralf Anderskewitz , Horst Dollinger , Dennis Fiegen , Thomas Fox , Rolf Goeggel , Christoph Hoenke , Domnic Martyres , Peter Nickolaus , Klaus Klinder
- 申请人地址: DE Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim am Rhein
- 代理商 Michael P. Morris; Timothy X. Witkowski
- 优先权: EP07118901 20071019
- 国际申请: PCT/EP2008/063999 WO 20081016
- 国际公布: WO2009/050248 WO 20090423
- 主分类号: C07D495/04
- IPC分类号: C07D495/04 ; A61K31/519 ; A61P29/00 ; A61P11/06 ; A61P25/28
摘要:
Piperidinodihydrothienopyrimidines of formula 1 wherein X is SO or SO2 (preferably SO), and R1, R2, R3, and R4 may have the meanings given in the disclosure and claims, pharmacologically acceptable salts thereof, and pharmaceutical compositions containing these compounds. These piperidinodihydrothienopyrimidines are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system, or cancers.
公开/授权文献
- US20110021501A1 SUBSTITUTED PIPERAZINO-DIHYDROTHIENOPYRIMIDINES 公开/授权日:2011-01-27
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