The combination of an over-the-road vehicle and a locking system. The vehicle has a frame bounding a cargo space and at least one access door. The one door has a first latch assembly thereon that cooperates with a second latch assembly on one of: a) the vehicle frame; and b) a second door to releasably maintain the one door in its closed position. The locking system includes a first locking assembly on the first door and a second locking assembly on the one of the vehicle frame and second door. The first locking assembly projects from a location between the first peripheral edge and the one of the vehicle frame and second door to beyond one of the inside and outside surfaces. The first and second locking assemblies can be maintained together either inside or outside of the cargo space.