发明授权
US08758757B2 Humanized antibodies to interferon alpha receptor-1 (IFNAR-1)
失效
干扰素α受体-1(IFNAR-1)的人源化抗体
- 专利标题: Humanized antibodies to interferon alpha receptor-1 (IFNAR-1)
- 专利标题(中): 干扰素α受体-1(IFNAR-1)的人源化抗体
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申请号: US12972813申请日: 2010-12-20
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公开(公告)号: US08758757B2公开(公告)日: 2014-06-24
- 发明人: Josephine M. Cardarelli , Tseng-hui Timothy Chen , David King , Christopher R. Bebbington , Sarah Lee Pogue , Francis J. Carr , Stephen Williams
- 申请人: Josephine M. Cardarelli , Tseng-hui Timothy Chen , David King , Christopher R. Bebbington , Sarah Lee Pogue , Francis J. Carr , Stephen Williams
- 申请人地址: US NJ Princeton
- 专利权人: Medarex, L.L.C.
- 当前专利权人: Medarex, L.L.C.
- 当前专利权人地址: US NJ Princeton
- 代理机构: Baker Botts L.L.P.
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/28 ; A61K39/00
摘要:
Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the humanized antibodies and therapeutic and diagnostic methods for using the humanized antibodies.
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