Invention Grant
- Patent Title: Method for measuring the activity of proteases
- Patent Title (中): 测定蛋白酶活性的方法
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Application No.: US12667960Application Date: 2008-07-07
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Publication No.: US08759019B2Publication Date: 2014-06-24
- Inventor: Hans Werner Hofer , Hans Jorg Meier
- Applicant: Hans Werner Hofer , Hans Jorg Meier
- Applicant Address: DE St. Georgen
- Assignee: Papst Licensing GmbH & Co. KG
- Current Assignee: Papst Licensing GmbH & Co. KG
- Current Assignee Address: DE St. Georgen
- Agency: Fitch, Even, Tabin & Flannery, LLP
- Priority: DE102007031706 20070706; DE102007033850 20070720
- International Application: PCT/DE2008/001104 WO 20080707
- International Announcement: WO2009/006877 WO 20090115
- Main IPC: C12Q1/37
- IPC: C12Q1/37
Abstract:
A method for determining the activity of proteases is provided. Fluorogenic substrates from which the fluorogen 7-amino-4-trifluoromethylcoumarin is eliminated proved to be particularly advantageous for the activity measurement. These substrates make it possible for measurement in microtiter plates with a fluorescence reader and thus for the fluorimetric determination of such enzyme activities in blood serum.
Public/Granted literature
- US20100267054A1 Measuring The Activity Of Proteases Public/Granted day:2010-10-21
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