发明授权
US08759342B2 Benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one urotensin II receptor antagonists
失效
苯并[1,4]恶嗪-3-酮，苯并[1,4]噻嗪-3-酮和喹啉-2-酮尿素调节素II受体拮抗剂
![Benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one urotensin II receptor antagonists](/docs/US/2014-06-24/US08759342B2/abs.jpg.600x600.jpg)
- 专利标题： Benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one urotensin II receptor antagonists
- 专利标题（中）： 苯并[1,4]恶嗪-3-酮，苯并[1,4]噻嗪-3-酮和喹啉-2-酮尿素调节素II受体拮抗剂
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申请号： US11881268申请日： 2007-07-26
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公开(公告)号： US08759342B2公开(公告)日： 2014-06-24
- 发明人: Ghosh Shyamali , William A Kinney , Edward C Lawson , Diane K Luci , Bruce E Maryanoff , Francois Maria Sommen
- 申请人： Ghosh Shyamali , William A Kinney , Edward C Lawson , Diane K Luci , Bruce E Maryanoff , Francois Maria Sommen
- 申请人地址： BE Beerse
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： BE Beerse
- 代理商 Yuriy P. Stercho
- 主分类号： A61K31/535
- IPC分类号： A61K31/535 ; C07D265/36
![Benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one urotensin II receptor antagonists](/abs-image/US/2014/06/24/US08759342B2/abs.jpg.150x150.jpg)
摘要：
The invention is directed to benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one Urotensin II receptor antagonists useful in treating or ameliorating a Urotensin-II mediated disorder. More specifically, the present invention relates to certain novel benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one compounds and methods for preparing compounds, compositions, intermediates and derivatives thereof. Pharmaceutical compositions and methods for treating or ameliorating a Urotensin-II mediated disorder using compounds of the invention are also described.
公开/授权文献
- US20080039454A1 Urotensin II receptor antagonists 公开/授权日：2008-02-14