发明授权
US08759541B2 Chiral acyclic diaminocarbene ligands, precursors therefore and their use in organic synthesis reactions
失效
因此手性非环状二胺碳配体,前体及其在有机合成反应中的用途
- 专利标题: Chiral acyclic diaminocarbene ligands, precursors therefore and their use in organic synthesis reactions
- 专利标题(中): 因此手性非环状二胺碳配体,前体及其在有机合成反应中的用途
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申请号: US13003039申请日: 2009-07-07
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公开(公告)号: US08759541B2公开(公告)日: 2014-06-24
- 发明人: Avinash N. Thadani , Rukundo Ntaganda , Mira M. Beshai
- 申请人: Avinash N. Thadani , Rukundo Ntaganda , Mira M. Beshai
- 代理机构: Bereskin & Parr LLP/S.E.N.C.R.L., s.r.l.
- 代理商 Michael Fenwick
- 国际申请: PCT/CA2009/000928 WO 20090707
- 国际公布: WO2010/003226 WO 20100114
- 主分类号: C07D207/09
- IPC分类号: C07D207/09 ; C07D403/04
摘要:
The current application relates to a metal catalyst of formula (I): M[ADC][X]n, wherein M is a metal, ADC is a chiral acyclic diaminocarbene ligand, and X is a neutral or anionic ligand. The ADC ligand is prepared from the corresponding chiral formamidium salt precursor. The metal catalyst is used for asymmetric organic synthesis reactions such as hydrosilations, hydrogenations, conjugate additions, and cross-couplings.
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