A receiver produces optimal weights for cancelling multipath interference. An SINR measurement module generates SINR measurements corresponding to soft symbol estimates produced by a baseband receiver from a received multipath signal. Each soft symbol estimate is replaced with either a hard estimate or a weighted soft estimate based on how each corresponding SINR measurement compares to a predetermined threshold. The received multipath signal and estimated interference signals generated from the hard symbol estimates and/or the weighted soft symbol estimates are combined to produce interference cancelled signals that may be combined via maximum ratio combining to produce an interference-cancelled MRC signal.