Invention Grant
- Patent Title: Therapeutic drug for adult T-cell leukemia
- Patent Title (中): 成人T细胞白血病治疗药物
-
Application No.: US13120114Application Date: 2009-08-20
-
Publication No.: US08765719B2Publication Date: 2014-07-01
- Inventor: Masanori Baba , Yuichi Hashimoto
- Applicant: Masanori Baba , Yuichi Hashimoto
- Applicant Address: JP Kagoshima
- Assignee: Kagoshima University
- Current Assignee: Kagoshima University
- Current Assignee Address: JP Kagoshima
- Agency: McCarter & English
- Priority: JP2008-242867 20080922; JP2008-256620 20081001; JP2009-068750 20090319
- International Application: PCT/JP2009/064557 WO 20090820
- International Announcement: WO2010/032582 WO 20100325
- Main IPC: A61K31/12
- IPC: A61K31/12 ; A61K31/166 ; A61K31/11 ; A61K31/695 ; A61K31/352 ; A61K31/095 ; A61K31/135 ; C07C49/83 ; C07C325/02 ; C07C233/65 ; C07C47/546 ; C07F7/08 ; C07C225/18

Abstract:
An object is to provide a novel therapeutic drug for adult T-cell leukemia having an ATL cell specific antitumor effect. The therapeutic drug for adult T-cell leukemia according to the invention is characterized by containing a compound represented by the formula I or a prodrug thereof, wherein R1 is H, OH, an alkoxy group, an acyl group, or a thioacyl group, R2 is an acyl group, a thioacyl group, CONR7R8, or CSNR7R8 (R7 and R8 being each independently H, an alkyl group containing 1 to 3 carbon atoms, or a phenyl group), or R1 and R2 together may form a ring, X1 and X2 may be the same or different and are each —CR3R4—, —SiR3R4— or oxygen, and R3 and R4 may be the same or different and are each an alkyl group containing 1 to 6 carbon atoms.
Public/Granted literature
- US20110172185A1 THERAPEUTIC DRUG FOR ADULT T-CELL LEUKEMIA Public/Granted day:2011-07-14
Information query