The invention relates to a method for operating a brake boosted brake system of a vehicle, comprising the monitoring of a mode of operation of the brake boosted brake system with regard to agreement of a total braking torque applied to at least one wheel of the vehicle by the brake boosted brake system with a specified target total braking torque and/or with regard to a displacement of a brake medium volume of the brake boosted brake system to a force/pressure conversion element (22) of the brake boosted brake system, if a braking torque difference between the applied total braking torque and the specified target total braking torque is greater than a specified reference difference, and/or if the brake medium volume displaced to the force/pressure conversion element (22) is larger than a specified reference volume; further comprising the defining of a target boosting force change with regard to a boosting force (Fu) provided by a brake booster (14) of the brake boosted brake system, taking into account the braking torque difference and/or the displaced brake medium volume, and outputting the target boosting force change to the brake booster (14). The invention further relates to a corresponding control device for a brake boosted brake system of a vehicle.