发明授权
- 专利标题: Compositions and methods for treatment
- 专利标题(中): 组合物和治疗方法
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申请号: US13011760申请日: 2011-01-21
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公开(公告)号: US08771715B2公开(公告)日: 2014-07-08
- 发明人: Johan Oslob , Wang Shen , Kenneth Barr , Min Zhong
- 申请人: Johan Oslob , Wang Shen , Kenneth Barr , Min Zhong
- 申请人地址: US CA Brisbane
- 专利权人: Sarcode Bioscience Inc.
- 当前专利权人: Sarcode Bioscience Inc.
- 当前专利权人地址: US CA Brisbane
- 代理机构: Troutman Sanders LLP
- 主分类号: A61K9/00
- IPC分类号: A61K9/00
摘要:
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists.
公开/授权文献
- US20110165228A1 Compositions and Methods for Treatment 公开/授权日:2011-07-07
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