发明授权
- 专利标题： β-Glucosidase variants
- 专利标题（中）： 葡萄糖苷酶变体
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申请号： US13375189申请日： 2010-06-16
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公开(公告)号： US08772010B2公开(公告)日： 2014-07-08
- 发明人: Xiyun Zhang , Jie Yang , Dipnath Baidyaroy , Sally Rhiannon Postlethwaite , Attila Andor , Louis Clark , Lisa M. Newman
- 申请人： Xiyun Zhang , Jie Yang , Dipnath Baidyaroy , Sally Rhiannon Postlethwaite , Attila Andor , Louis Clark , Lisa M. Newman
- 申请人地址： US CA Redwood City
- 专利权人： Codexis, Inc.
- 当前专利权人： Codexis, Inc.
- 当前专利权人地址： US CA Redwood City
- 代理机构： Codexis, Inc.
- 国际申请： PCT/US2010/038902 WO 20100616
- 国际公布： WO2010/148148 WO 20101223
- 主分类号： C12N9/42
- IPC分类号： C12N9/42 ; C12N9/14 ; C12N9/24 ; C12N9/00
摘要：
The invention relates to recombinantly produced β-Glucosidase Variants with enhanced thermoactivity compared to naturally occurring proteins. The invention also provides methods for producing a variant β-glucosidase polypeptide with improved thermoactivity by identifying performance sensitive positions in a target β-glucosidase polypeptide and substituting the residue at that position with a thermoactivity enhancing residue.
公开/授权文献
- US20120077216A1 Beta-Glucosidase Variants 公开/授权日：2012-03-29
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