Invention Grant
US08772238B2 Use of ixolaris, a tissue factor inhibitor, for the treatment of cancer
有权
使用ixolaris，组织因子抑制剂治疗癌症
- Patent Title: Use of ixolaris, a tissue factor inhibitor, for the treatment of cancer
- Patent Title (中): 使用ixolaris，组织因子抑制剂治疗癌症
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Application No.: US13257455Application Date: 2010-03-18
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Publication No.: US08772238B2Publication Date: 2014-07-08
- Inventor: Ivo M. B. Francischetti , Robson de Queiroz Monteiro , Jose Marcos C. Ribeiro
- Applicant: Ivo M. B. Francischetti , Robson de Queiroz Monteiro , Jose Marcos C. Ribeiro
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Edwards Wildman Palmer LLP
- Agent Peter F. Corless
- International Application: PCT/US2010/027797 WO 20100318
- International Announcement: WO2010/107991 WO 20100923
- Main IPC: A61K38/57
- IPC: A61K38/57 ; A61K38/00 ; C07K14/00
Abstract:
The invention provides methods for treatment of tissue factor (TF) mediated or associated diseases or processes, such as cancer, by administering at least an active fragment of an Ixolaris polypeptide to a subject. The invention further includes identification of a subject in need of such treatment, and monitoring a subject for amelioration of at least one sign or symptom of the disease. The invention also features kits.
Public/Granted literature
- US20120010137A1 USE OF IXOLARIS, A TISSUE FACTOR INHIBITOR, FOR THE TREATMENT AND PREVENTION OF CANCER Public/Granted day:2012-01-12
Information query
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