发明授权
- 专利标题： Preventive or therapeutic agent for fibrosis
- 专利标题（中）： 纤维化的预防或治疗剂
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申请号： US13824080申请日： 2011-10-14
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公开(公告)号： US08772262B2公开(公告)日： 2014-07-08
- 发明人: Esteban C Gabazza , Tetsu Kobayashi , Hidekazu Toyobuku , Ayako Fukuda , Tetsuya Hasegawa
- 申请人： Esteban C Gabazza , Tetsu Kobayashi , Hidekazu Toyobuku , Ayako Fukuda , Tetsuya Hasegawa
- 申请人地址： JP Tsu-shi JP Tokyo
- 专利权人： Mie University,Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人： Mie University,Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人地址： JP Tsu-shi JP Tokyo
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权： JP2010-231946 20101014
- 国际申请： PCT/JP2011/073628 WO 20111014
- 国际公布： WO2012/050181 WO 20120419
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C07H21/04
摘要：
Provided is siRNA effective for the treatment of fibrosis and a pharmaceutical containing the siRNA. An siRNA having a full length of 30 or fewer nucleotides and targeting a sequence consisting of 17 to 23 consecutive bases selected from the group consisting of bases at positions 1285 to 1318, bases at positions 1398 to 1418, bases at positions 1434 to 1463, bases at positions 1548 to 1579, bases at positions 1608 to 1628, bases at positions 1700 to 1726, bases at positions 1778 to 1798, bases at positions 1806 to 1826, and bases at positions 1887 to 1907 of SEQ ID NO: 1.
公开/授权文献
- US20130217754A1 PREVENTIVE OR THERAPEUTIC AGENT FOR FIBROSIS 公开/授权日：2013-08-22
信息查询
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