发明授权
US08772463B2 Fluorescent dye-labeled glucose bioprobe, synthesis method and usage thereof
有权
荧光染料标记的葡萄糖生物探针,其合成方法和用途
- 专利标题: Fluorescent dye-labeled glucose bioprobe, synthesis method and usage thereof
- 专利标题(中): 荧光染料标记的葡萄糖生物探针,其合成方法和用途
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申请号: US12876520申请日: 2010-09-07
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公开(公告)号: US08772463B2公开(公告)日: 2014-07-08
- 发明人: Seung Bum Park , Hyang Yeon Lee , Jong Min Park
- 申请人: Seung Bum Park , Hyang Yeon Lee , Jong Min Park
- 申请人地址: KR Seoul
- 专利权人: SNU R&DB Foundation
- 当前专利权人: SNU R&DB Foundation
- 当前专利权人地址: KR Seoul
- 代理机构: Hamre, Schumann, Mueller & Larson, P.C.
- 优先权: KR10-2007-0029334 20070326; KR10-2009-0084068 20090907; KR10-2010-0024274 20100318
- 主分类号: C07H17/02
- IPC分类号: C07H17/02
摘要:
Disclosed are a novel fluorescent glucose analogue, a method for the synthesis thereof and the use thereof. The novel fluorescent glucose analogue is labeled with fluorescent dye by O-1-glycosylation and via various linkers. The fluorescent glucose analogue can be applied to molecular bioimaging and a method for screening curative or preventive drugs for glucose metabolism-related diseases.
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