发明授权
- 专利标题: PDE10 modulators
- 专利标题(中): PDE10调制器
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申请号: US13598848申请日: 2012-08-30
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公开(公告)号: US08772510B2公开(公告)日: 2014-07-08
- 发明人: Stephan Bachmann , Alexander Flohr , Katrin Groebke Zbinden , Matthias Koerner , Bernd Kuhn , Jens-Uwe Peters , Markus Rudolph
- 申请人: Stephan Bachmann , Alexander Flohr , Katrin Groebke Zbinden , Matthias Koerner , Bernd Kuhn , Jens-Uwe Peters , Markus Rudolph
- 申请人地址: US NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Nutley
- 优先权: EP11180135 20110906
- 主分类号: C07D249/04
- IPC分类号: C07D249/04 ; C07D233/54 ; C07D231/10 ; C07D207/30
摘要:
The present invention relates to compounds of formula (I) wherein R1, R2, R3, R5, W, X, X1, Y, Y1, Z and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit PDE10A and can be used in the treatment of CNS disorders such as schizophrenia, Alzheimer's disease, and Parkinson's disease.
公开/授权文献
- US20130059833A1 PDE10 MODULATORS 公开/授权日:2013-03-07
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