Invention Grant
US08778361B2 Canine tumor cell and allogeneic dendritic cell fused vaccine and method for preparing the same
有权
犬肿瘤细胞和同种异体树突细胞融合疫苗及其制备方法
- Patent Title: Canine tumor cell and allogeneic dendritic cell fused vaccine and method for preparing the same
- Patent Title (中): 犬肿瘤细胞和同种异体树突细胞融合疫苗及其制备方法
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Application No.: US12483735Application Date: 2009-06-12
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Publication No.: US08778361B2Publication Date: 2014-07-15
- Inventor: Rea-Min Chu , Chien-Chun Pai , Tien-Fu Chuang
- Applicant: Rea-Min Chu , Chien-Chun Pai , Tien-Fu Chuang
- Applicant Address: TW Taipei
- Assignee: National Taiwan University
- Current Assignee: National Taiwan University
- Current Assignee Address: TW Taipei
- Agency: WPAT, P.C.
- Agent Anthony King
- Priority: TW98107651A 20090309
- Main IPC: A61K35/14
- IPC: A61K35/14 ; C12N5/0784 ; C12N5/09 ; C12N5/16 ; C12N15/06 ; A61K39/00
Abstract:
The present invention provides a dendritic cell-based vaccine by fusing a canine tumor cell and an allogeneic dendritic cell, and a method for preparing the same. The fusion cells expressing canine tumor antigens are generated by fusing canine bone marrow-derived dendritic cells and canine tumor cells. The canine immune system can be induced to produce tumor specific T lymphocytes and natural killer cells when the fusion cells used as a vaccine is injected into a canine body.
Public/Granted literature
- US20100227395A1 CANINE TUMOR CELL AND ALLOGENEIC DENDRITIC CELL FUSED VACCINE AND METHOD FOR PREPARING THE SAME Public/Granted day:2010-09-09
Information query
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