The antenna matching circuit control device with an antenna body includes a sensing module, a processing module, a power adjusting module and a frequency adjusting module. The sensing module senses an object that approaches the antenna body and outputs a sensing signal accordingly. The processing module is coupled to the sensing module and outputs a first control signal and a second control signal according to the sensing signal. The power adjusting module is coupled to the processing module and controls a power amplifier to couple with one of a plurality of first matching circuits according to the first control signal. The frequency adjusting module is coupled to the antenna body and the power adjusting module. The frequency adjusting module controls one of a plurality of second matching circuits to couple with one of the first matching circuits according to the second control signal.